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Danish trial icd

WebOct 11, 2007 · Clinical Trial NCT00542945; Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH) July 16, 2024 updated by: ... Risk Models for Prediction of Implantable Cardioverter-Defibrillator Benefit: Insights From the DANISH Trial. JACC Heart Fail. 2024 Aug;7(8):717-724. doi: 10.1016/j.jchf.2024.03.019. Epub 2024 Jul 10. WebA total of 229 patients were randomly assigned to receive standard medical therapy, and 229 to receive standard medical therapy plus a single-chamber ICD. Results Patients were followed for a...

Frontiers Implantable Cardioverter-Defibrillator in Dilated ...

WebAug 13, 2024 · In contrast, the more recent randomized Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) trial investigated the role of primary prevention ICDs exclusively in non-ischemic cardiomyopathy; it demonstrated a significant reduction in sudden cardiac death in … WebSep 29, 2016 · In this trial, prophylactic ICD implantation in patients with symptomatic systolic heart failure not caused by coronary artery disease was not associated with a … high st rockport https://forevercoffeepods.com

Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH)

WebNov 12, 2024 · Life-threatening ventricular arrhythmias, including sustained ventricular tachycardia (VT) and ventricular fibrillation (VF), are common in patients with systolic heart failure (HF) and dilated cardiomyopathy and may lead to sudden cardiac death (SCD). WebDec 3, 2024 · The 2016 Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) randomized 1116 patients … WebJan 18, 2024 · While ICD therapy is indicated for patients with both ICM and NICM, support for the ICD in primary prevention of sudden cardiac death is much stronger for patients with the ischemic disease. Prior pooled analyses of randomized trials showed benefits of an ICD in the setting of nonischemic disease, but the most recent study (DANISH) did not ... high st rochester

Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH)

Category:Implantable Cardioverter-Defibrillator for Primary Prevention in Asia

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Danish trial icd

Devices in Heart Failure Patients—Who Benefits From ICD and …

WebSep 22, 2024 · This was a prespecified subgroup analysis of the 1,116 patients from the DANISH (Danish Study to Assess the Efficacy of ICDs in Patients with Non … WebNov 25, 2024 · Recent findings: Recent studies including the Danish study to assess the efficacy of ICDs in patients with non-ischemic systolic heart failure on mortality …

Danish trial icd

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WebJun 18, 2024 · To the Editor: Elming et al 1 report that the efficacy of primary prevention implantable cardioverter-defibrillator (ICD) therapy is diminished among older participants of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality), which randomized patients with … WebAug 29, 2024 · In the DANISH trial, patients in the medical therapy and ICD arms were also stratified according to CRT implantation status; survival was not statistically different in the ICD group as compared to medical therapy in patients who had CRT device implanted (HR 0.91, 95% CI 0.64–1.29, P=0.59) or those who did not (HR 0.83, 95% CI 0.58–1.19, …

WebIntroduction: With the recent publication of the negative DANISH trial, the mortality benefit of the implantable cardioverter-defibrillator (ICD) has been put in question in patients with non-ischemic cardiomyopathy (NICM). WebApr 18, 2024 · The DANISH study therefore seems to already have had a high impact on clinical decision making for primary prevention ICD in the medical community. Only 40% of centres reported to implant primary prevention ICD in >75% of all patients with non-ischaemic disease fulfilling current recommendations.

WebJun 1, 2024 · Of course, the standard heart failure regimen of neither DANISH nor COMPANION trial included sacubitril/valsartan and sodium-glucose cotransporter-2 inhibitors, and it is not known how these recent pharmacological advances may differentially affect outcomes of patients with CRT-D versus CRT-P.

WebAug 28, 2016 · In the Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality (DANISH) of about 1100 symptomatic patients with an LVEF < 35 on optimal meds...

WebMar 14, 2024 · In this post hoc analysis of the DANISH trial (Danish Study to Assess the Efficacy of ICDs in Patients with Nonischemic Systolic Heart Failure on Mortality), patients with nonischemic systolic heart … high st rdWebAccording to current guidelines prophylactic implantable cardioverter-defibrillator (ICD) therapy is recommended in patients with significantly impaired left ventricular systolic function. However, the recently published DANISH trial did not find a significantly lower long-term rate of death from an … Can we rely on Danish? Heart Vessels. how many days since may 26th 2021WebMay 19, 2024 · In 2016, the DANISH trial, largest trial addressing this topic, was published including 1116 symptomatic NICM patients followed up for a mean period of 67.6 months. The DANISH trial showed no significant difference between the ICD group and optimal medical therapy (OMT) group as regards the primary outcome of all-cause mortality. high st runwayWebMar 7, 2024 · Treatment with ICD was associated with a 23% risk reduction for all-cause mortality, and a 57% risk reduction for SCD. 48 These findings, together with the findings from the DANISH trial (great advantage in patients <70 years or those without diabetes), highlight the need for improved patient selection when referring patients with NICM for an ... how many days since may 30 2022WebAug 28, 2016 · The Danish ICD Study in Patients With Dilated Cardiomyopathy (DANISH) delivers two important lessons: the specific one deals with ICD use in patients with heart … high st service danversWebFeb 1, 2024 · Similarly to the RR, the risk difference of SCD for ICD patients with respect to controls showed a progressive increase, from negative values of −9.7% and −18.0% in the MADIT and MUSTT trials to −3.9% in the DANISH trial (R 2 = 0.53, p = 0.06), which indicated a progressive decrease of the efficacy of ICD therapy. how many days since may 2nd 2022WebMar 29, 2024 · More recently the DANISH 2 (Danish ICD Study in Patients with Dilated Cardiomyopathy) study, ... (from 6% per year reported by the DEFINITE trial, to 2.1% per year of the DANISH study 2, 4). Furthermore, the incidence of inappropriate shocks is not negligible, despite the technological improvements of the devices, (10% DEFINITE; 10% … high st salem or