Ctr copper transporter family protein

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August undefined, 2024

WebCenter for Biotechnology & Drug Design (CDBB) Institution: Georgia State University URL: http://www.biology.gsu.edu/BDD/index.html Description: vaccines, drug design ... WebFeb 1, 2024 · Furthermore, protein–protein interactions (PPI) analysis combined with validation experiments showed that the combination of AgNPs and domiphen could enhance the expression of copper transporter and inhibit nitrogen source metabolism.

Structural and Functional Diversity Among the Members of CTR…

WebJun 30, 2024 · COPT, a conserved family of membrane proteins that function as copper transporters, can cope with copper deficiency and excess. In addition to Cu transport, … WebFeb 8, 2002 · This is the first report on the biochemical characterization of the human copper transporter hCtr1, which is important for understanding mechanisms for mammalian copper transport at the plasma membrane. The trace metal copper is an essential cofactor for a number of biological processes including mitochondrial oxidative … the plot in you band members

A differential subcellular localization of two copper ... - ScienceDirect

WebDec 1, 2015 · The COPT/Ctr family belongs to a highly conserved Ctr-like Cu transporter family. Most COPT/Ctr transporters contain 3 TMDs: TMD1, TMD2, and TMD3. The N terminus of most COPT/Ctr transporters includes methionine motifs involved in Cu binding that is important for facilitated import (Beaudoin et al., 2011). Webthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights … WebApr 21, 2011 · The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Results: All members of the rice COPT family have the conserved features of known COPT/Ctr-type Cu transporter genes. sideswipe collision injuries

The SLC31 (Ctr) copper transporter family - PubMed

WebRecently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in … WebSep 12, 2007 · High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its function in copper uptake is currently unknown. To characterize the role of hCTR2 in copper homoeostasis, epitope-tagged hCTR2 was transiently … sides with brisket dinnerWebGene name : SLC31A1. Family name : Copper transporter (Ctr) (TC 1.A.56) >>. SLC31A. Entry whose protein (s) existence is based on evidence at protein level. Show evidences. Annotations in this section apply to all the isoforms if not specified otherwise. the plot in you concert

"WebMar 1, 2004 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … " - Ctr copper transporter family protein

Ctr copper transporter family protein

Biochemical Characterization of the Human Copper Transporter …

WebApr 11, 2024 · Arabidopsis copper transport protein COPT2 participates in the cross talk between iron deficiency responses and low-phosphate signaling. Plant Physiol., 162 (2013), ... Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol., 11 (2011), p. 69. View in Scopus Google Scholar WebStudies were conducted to determine distribution of the copper transporter, Ctr1, a transmembrane protein responsible for cellular copper uptake, in adult mice and in …

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WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69 WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. …

WebJul 21, 2014 · The family of proteins responsible for the transport of Cu in the reduced form is the COPT transport protein (copper transporter protein). These proteins are formed by five... WebApr 21, 2011 · The copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Here we report the …

WebJul 24, 2024 · Naturally, this localization of the receptors requires the transport of monovalent copper from the plasma membrane via the cytoplasm to the apoproteins in the ER-Golgi membranes. The identity of the copper carriers involved in this task and their cellular routes are not yet completely known. WebJan 5, 2024 · COPT5copper transporter 5 [ Arabidopsis thaliana(thale cress) ] Gene ID: 832188, updated on 5-Jan-2024 Download Datasets Gene Sequences (FASTA) …

WebNov 1, 2006 · CTR1 belongs to the CTR (or SLC31A) family that includes CTR1/2 and P-type copper transporting ATPases (ATP7A and B). It is a 23-kDa channel-like transporter which has a unique pore for the transport of copper and three trans-membranes domains that oligomerize to form a functional trimer [85].

WebOct 19, 2015 · These transport proteins are thought to have evolved from ‘half-transporters’ containing a single repeat via gene duplication and subsequent fusion 28. … the plot in you membersWebAAA Cooper Transportation offers an excellent opportunity for employees across a breadth of skills, experience, and backgrounds. Click the careers button to find out more about … the plot in you album coverWebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... the plot in you lead singerWebCtr copper transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress … the plot in you wife beaterWebCopper uptake is regulated by CTR (copper transporter) family of proteins, which are highly conserved. High affinity copper uptake is facilitated by Ctr1 and Ctr3 in Saccharomyces cerevisiae and ... the plot in you tour datesWebSep 25, 2024 · CTR1 belongs to a family of Copper Transporters that has at least six members (CTR1-6) among various organisms. Structural and functional divergence of the CTRs from lower organisms to mammals shed light on how the regulation of this protein family is modulated depending on the requirement and availability of copper. the plot jean hanff korelitz spoilersWebApr 2, 2014 · Some pieces of evidence reported that Cu can be also taken up by other bivalent cations transporters, as the Natural Resistance Associated Macrophage Proteins (NRAMP), Zrt-and Irt-like proteins... the plotkin group